A 6-Year-Old Male Weighing 50 Lbs Presents Complaining Of A
A 6 Year Old Male Weighing 50 Lbs Presents Complaining Of A Sore Throa
A 6-year-old male weighing 50 lbs presents with a sore throat and has a positive rapid strep test. He will be treated with amoxicillin (Amoxil®) with a dosing of 50 mg/kg/day. Calculate the total milligrams per day for this patient, rounding to the nearest 5 mg. Then, determine how many milliliters this dosage corresponds to using a concentration of 400 mg/5 mL, rounded to the nearest 0.5 mL.
A 2-month-old infant weighing 9 lbs presents with erosive esophagitis. The prescribed treatment is ranitidine (Zantac®) at 10 mg/kg/day, divided into two doses. Ranitidine is available at a concentration of 15 mg/mL. Calculate the volume in milliliters for each dose, rounding to the nearest 0.1 mL. For a 30-day supply, determine the total volume in mL needed, rounding to the nearest 5 mL, ensuring enough medication for the entire period.
A mother of a 4-year-old child weighing 30 lbs calls seeking dosing recommendations for ibuprofen (Motrin®) to reduce fever. The recommended dose range is 5-10 mg/kg every 6-8 hours as needed. The ibuprofen suspension has a concentration of 100 mg/5 mL. Calculate the appropriate dose range in milliliters for each administration, rounding to the nearest 0.5 mL.
The mother prefers to use acetaminophen (Tylenol®) instead. The dosing recommendation is 10-15 mg/kg per dose. The suspension is available at 160 mg/5 mL. Determine the suitable dose range in milliliters for each dose, rounding to the nearest 0.1 mL.
Paper For Above instruction
Appropriate pediatric dosing is essential to ensure efficacy while minimizing potential toxicity or adverse effects. Calculations based on weight are common, and precise measurement is crucial. This paper discusses the calculations requested for specific pediatric patients, including the dosage and volume determinations for amoxicillin, ranitidine, ibuprofen, and acetaminophen, based on their weights and medication concentrations.
Amoxicillin Dosing for a 6-Year-Old Male
The patient is a 6-year-old male weighing 50 lbs. Converting pounds to kilograms (kg) is necessary because pediatric dosages are typically calculated based on weight in kg. Using the conversion factor 1 kg = 2.2 lbs, the child's weight in kg is:
50 lbs / 2.2 = 22.73 kg
The prescribed dose is 50 mg/kg/day. Therefore, the total daily dose in milligrams is:
50 mg/kg/day × 22.73 kg ≈ 1,136.5 mg
Rounding to the nearest 5 mg, the daily dose is:
1,135 mg/day
To determine the volume in milliliters using a concentration of 400 mg/5 mL, we set up the proportion:
(400 mg / 5 mL) = (1,135 mg / x mL)
x = (1,135 mg × 5 mL) / 400 mg ≈ 14.19 mL
Rounded to the nearest 0.5 mL, the dose per day is:
14.0 mL
Ranitidine Dose for a 2-Month-Old Infant
The infant weighs 9 lbs. Converting to kg:
9 lbs / 2.2 ≈ 4.09 kg
The total daily dose is 10 mg/kg/day:
10 mg/kg × 4.09 kg ≈ 40.9 mg/day
Divided into two doses, each dose is approximately 20.45 mg. Using a concentration of 15 mg/mL, the volume per dose is:
(20.45 mg / 15 mg/mL) ≈ 1.36 mL
Rounded to the nearest 0.1 mL, each dose is:
1.4 mL
For a 30-day supply, total volume needed is:
40.9 mg/day × 30 days = 1,227 mg
Total volume = (1,227 mg / 15 mg/mL) ≈ 81.8 mL
Rounded to the nearest 5 mL, the supply is:
80 mL
Ibuprofen Dosing for a 4-Year-Old Child
The child's weight is 30 lbs. Converting to kg:
30 lbs / 2.2 ≈ 13.64 kg
The recommended dose range is 5-10 mg/kg:
Lower end: 5 mg/kg × 13.64 kg ≈ 68.2 mg
Upper end: 10 mg/kg × 13.64 kg ≈ 136.4 mg
Using the concentration 100 mg/5 mL, the volume range per dose is:
- Lower dose: (68.2 mg / 100 mg) × 5 mL ≈ 3.41 mL
- Upper dose: (136.4 mg / 100 mg) × 5 mL ≈ 6.82 mL
Rounded to the nearest 0.5 mL:
- Lower dose: 3.5 mL
- Upper dose: 6.5 mL
Acetaminophen Dosing for the Same Child
Using the recommended dose range of 10-15 mg/kg per dose, the calculations are:
Lower end: 10 mg/kg × 13.64 kg ≈ 136.4 mg
Upper end: 15 mg/kg × 13.64 kg ≈ 204.6 mg
Given the concentration 160 mg/5 mL, the volume per dose is:
- Lower dose: (136.4 mg / 160 mg) × 5 mL ≈ 4.26 mL
- Upper dose: (204.6 mg / 160 mg) × 5 mL ≈ 6.39 mL
Rounded to the nearest 0.1 mL, the doses are:
- 4.3 mL (lower)
- 6.4 mL (upper)
Conclusion
Accurate calculations based on weight and medication concentration ensure effective pediatric treatment. The doses determined here align with standard pediatric dosing guidelines and emphasize the importance of precise measurement, especially in children, to avoid underdosing or overdosing. Healthcare providers must always verify calculations and consider individual patient factors in clinical practice.
References
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- American Academy of Pediatrics. (2021). Pediatric medication dosing. Pediatrics, 147(2), e2021050957.
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- U.S. Food & Drug Administration. (2023). Pediatric drug labeling. FDA.gov.
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