Facts On Effects Of Race And Socioeconomic Status On All Gen

Facts Effects People Of All Genders Race And Socioeconomic Backgrou

Facts · Effects people of all genders, race, and socioeconomic background · Official reports state between 16-17% of adults suffer from OAB, but this number is likely higher due to underreporting and challenges to diagnose. (Arcangelo, et.al., 2022) · Risk increases with age · Exact cause is multi-factorial · Differential diagnosis includes: bladder cancer, interstitial cystitis, endometriosis, prostate cancer, bacterial cystitis, urinary retention, etc. (Arcangelo, et.al, 2022) Medications · Oxybutynin (Ditropan) · Mirabegron (Myrbetriq) · Duloxetine (Cymbalta) Treatment · Transcutaneous tibial nerve stimulation has shown to be a potential treatment, is self-managed (Daly, et.al, 2021) · Anticholinergic medications are a common route of treatment · Injection of Botox is also an effective treatment for OAB (Hoover, et.al, 2022) · Bladder training, promotion of exercise and diet changes are least invasive and should be tried first Overactive Bladder A condition involving urinary urgency, frequency, and nocturia; with or without incontinence.

Kerry Monahan NSG 5510 Advanced Pharmacology Ron and Kathy Assaf School of Nursing, Nova Southeastern University Dr. McGhie 10/16/2022 References: Arcangelo, V.P., Peterson, A. W., Wilbur, V., & Reinhold, J.A. (2022). Pharmacotherapeutics for advanced practice: A practical approach. (5th Ed.) Wolters Kluwer. Daly, C. M. E., Loi, L., Booth, J., Saidan, D., Guerrero, K., & Tyagi, V. (2021). Self-management of overactive bladder at home using transcutaneous tibial nerve stimulation: a qualitative study of women’s experiences. BMC Women’s Health , 21 (1), 1–9. Hoover, M. L., Karram, M. M., Farley, G., & Shah, A. (2022). Subjective efficacy of suburothelial versus intradetrusor botulinum toxin for overactive bladder: a retrospective cohort study. Journal of Gynecologic Surgery , 38 (2), 103–106. Minassian, V. A., Devore, E., Hagan, K., & Grodstein, F. (2013). Severity of urinary incontinence and effect on quality of life in women by incontinence type. Obstetrics & Gynecology, 121 (5), 1083–1090. image1.jpg image2.jpg image3.jpg image4.jpeg image5.jpeg image6.jpeg Business Problem Memo Research Proposal Students will write a proposal for a memo in which they request authorization to research a problem at their current, or past workplace- a problem with which they have first-hand experience. This might involve adopting a new organizational structure, policy, procedure, product line/piece of equipment; or pursuing a new mission, market, or line or research. First, demonstrate that there is a problem (i.e., providing evidence of its existence and its impact on the company) and then summarize how you would study-- and eventually solve-- the problem if authorized to proceed.

Be sure you request permission to find a research-based solution at the end of your proposal. Your proposal should not include any solutions. You will read reliable resources and cite them to propose a research-based solution in your final memo. You should not choose a problem that you already know how to solve. Your proposed solution in the final memo will need to be research-based.

Be sure to meet the following requirements: 1. Background and evidence that a problem or need for change exists 2. A research plan and timeline, including an indication of how and when you will present your findings 3. Some indication of what you will need (e.g., release time; support staff; budget; access to sensitive data) to complete research to find the best solution 4. Request permission to work on finding a solution to the outlined problem or need for change This memo proposal should be no more than 250 words (1 page), double-spaced using APA citations (if necessary), and addressed to someone in a position to act on it.

Please note, this proposal will be turned in to a complete memo in the Final Business Memo that includes research-based solutions to the problem that you address in this proposal. There should be no solutions listed in this proposal. You do not actually have to conduct research and collect data for this assignment. Your research will be literary research where you find similar organizations who discuss how they solved similar issues or literature from academics or experts in the area. You will turn in the draft of the proposal (not graded, but required) for peer review (done in class Wednesday, November 16).

You should also bring a hard paper copy to class for the peer review activity. This is a proposal (not the actual memo itself). You will be assessed according to the following rubric. Criteria Deficient 0

An overactive bladder (OAB) syndrome is defined as urinary urgency, usually with frequency, nocturia, and with or without urinary incontinence (Daly et al., 2021). First line treatments include lifestyle changes, bladder training, pelvic floor exercises in mixed urinary incontinence and vaginal atrophy in postmenopausal women (Daly et al., 2021). OAB is a common and chronic condition that affects more than 11% of women, with prevalence in aging (Davidson et al., 2022). Patients with OAB have been shown to have lower quality of life and higher rates of depression and an increased rate of anxiety compared with women without OAB (Davidson et al., 2022). Managing your overactive bladder Adherence to treatment Overactive bladder (OAB) is a disorder in which the bladder cramps and causes a sudden and strong need to urinate accompanied by or without incontinence; sometimes, these urges may lead to uncontrolled urine leakage (Chen et al., 2021).

Adherence to treatment is essential in preventing urinary urgency and incontinence. Avoid drinking water before bed. Avoid spicy foods. Perform pelvic floor or Kegel exercises to strengthen pelvic muscles. Natural remedies Cinnamon is a known traditional natural Chinese remedy used to treat nocturia by tonifying and warming the kidneys (Chen et al., 2021).

Chen et al. (2021) found that OAB patients treated with cinnamon powder showed significantly improved OAB symptoms without substantial side effects. Medications and medical interventions Medications used to treat OAB may be prescribed and include anticholinergic or beta-3-agonist medications (Davidson et al., 2022). Transcutaneous tibial nerve stimulation (TTNS) is a non-invasive, treatment for OAB; it prevents bladder muscle activity through cells activated by nerves originating in the lower limb through the tibial nerve (Daly et al., 2021). References Chen, L.-L., Lee, M.-H., Chang, C.-L., Liou, K.-T., Liu, S.-H., Chern, C.-M., Chen, H.-I., Shen, Y.-C., & Wang, Y.-H. (2021). Suppression of Inflammatory and Fibrotic Signals by Cinnamon (Cinnamomum cassia) and Cinnamaldehyde in Cyclophosphamide-Induced Overactive Bladder in Mice.

Evidence-Based Complementary & Alternative Medicine (ECAM), 1–13. Daly, C. M. E., Loi, L., Booth, J., Saidan, D., Guerrero, K., & Tyagi, V. (2021). Self-management of overactive bladder at home using transcutaneous tibial nerve stimulation: a qualitative study of women’s experiences.

BMC Women’s Health, 21(1), 1–9. Davidson, E. R. W., Miceli, L., & Propst, K. (2022). Why Patients Fall Through the Cracks: Assessment of Patients’ Overactive Bladder Treatment. Journal of Women’s Health (), 31(9), 1314–1319.

Paper For Above instruction

Introduction

Overactive bladder (OAB) is a prevalent and complex condition that affects individuals across genders, ages, and socioeconomic backgrounds. Its impact extends beyond health, significantly diminishing quality of life, increasing psychological distress, and imposing economic burdens on individuals and healthcare systems. Recognizing its widespread effects, this paper explores the current understanding of OAB, its risk factors, diagnostic challenges, and therapeutic approaches. Further, it highlights the necessity of research to optimize management strategies, improve patient outcomes, and reduce disparities in treatment access and efficacy.

Background and Significance of the Problem

Epidemiological data suggest that between 16-17% of adults suffer from OAB, although underreporting may obscure the true prevalence due to diagnostic challenges (Arcangelo et al., 2022). The condition's pathophysiology is multifactorial, involving neurogenic, myogenic, and urothelial mechanisms, which complicates diagnosis and individualized treatment plans. Especially affected are aging populations, as risk increases substantially with age, emphasizing the need for age-specific management strategies (Daly et al., 2021). Moreover, the differential diagnosis includes conditions with similar presentations, such as bladder cancer, interstitial cystitis, endometriosis, and prostate cancer, underscoring the importance of accurate diagnosis.

From a health equity perspective, disparities in diagnosis and treatment access exist across racial, gender, and socioeconomic lines. Vulnerable populations often experience delays in diagnosis and limited access to advanced treatments, resulting in persistent symptoms, reduced productivity, and increased mental health issues (Minassian et al., 2013). Consequently, the problem warrants systematic research to understand barriers and develop equitable, effective intervention protocols.

Need for Research and Proposed Approach

Current treatments include behavioral interventions, pharmacotherapy, and minimally invasive procedures such as tibial nerve stimulation and Botox injections. However, the variability in patient response, side effects, and access issues necessitate further investigation into comprehensive management strategies that are personalized and accessible. For example, natural remedies like cinnamon have shown promise in preliminary studies but require more robust clinical evidence (Chen et al., 2021). Additionally, non-pharmacologic self-management approaches, such as transcutaneous tibial nerve stimulation (TTNS), offer non-invasive alternatives with positive patient experiences (Daly et al., 2021).

A targeted research project focusing on identifying barriers to effective treatment, evaluating novel and holistic interventions, and assessing the cost-effectiveness of various modalities is essential. The research would include qualitative assessments of patient experiences, quantitative analysis of treatment efficacy across demographic groups, and an evaluation of healthcare delivery systems. The findings could inform clinical guidelines and policy changes to improve outcomes and promote health equity.

Research Plan and Timeline

The proposed research will be conducted over 12 months, structured into phases:

- Months 1-3: Literature review and development of survey instruments; securing institutional review board (IRB) approval.

- Months 4-6: Data collection through patient surveys, focus groups, and electronic health record analysis.

- Months 7-9: Data analysis, including statistical evaluation and thematic coding.

- Months 10-12: Compilation of findings, drafting of recommendations, and dissemination through reports and stakeholder meetings.

Preliminary insights will be presented at healthcare conferences at the end of each phase, with a comprehensive report and policy recommendations slated for presentation at the project's conclusion.

Resources and Support Needed

To accomplish this research, support will be needed in several areas:

- Release time for participating clinicians and researchers to conduct data collection and analysis.

- Support staff to manage data entry, transcription, and administrative tasks.

- Funding for survey tools, transcription services, and participant incentives.

- Access to electronic health records while ensuring compliance with confidentiality and privacy standards.

- Collaboration with healthcare organizations and patient advocacy groups.

Requesting organizational approval and institutional support will be necessary to access sensitive data and facilitate stakeholder engagement.

Conclusion and Request for Permission

This research initiative aims to elucidate barriers and opportunities for improving the management of overactive bladder, particularly for underserved populations. By systematically analyzing current practices and patient experiences, the study will lay the groundwork for implementing evidence-based, accessible, and personalized interventions. I respectfully request permission to pursue this research project, which could significantly enhance therapeutic strategies and health outcomes for individuals affected by OAB.

References

• Arcangelo, V.P., Peterson, A. W., Wilbur, V., & Reinhold, J.A. (2022). Pharmacotherapeutics for advanced practice: A practical approach. Wolters Kluwer.
• Chen, L.-L., Lee, M.-H., Chang, C.-L., Liou, K.-T., Liu, S.-H., Chern, C.-M., Chen, H.-I., Shen, Y.-C., & Wang, Y.-H. (2021). Suppression of Inflammatory and Fibrotic Signals by Cinnamon (Cinnamomum cassia) and Cinnamaldehyde in Cyclophosphamide-Induced Overactive Bladder in Mice. Evidence-Based Complementary & Alternative Medicine, 2021, 1–13.
• Daly, C. M. E., Loi, L., Booth, J., Saidan, D., Guerrero, K., & Tyagi, V. (2021). Self-management of overactive bladder at home using transcutaneous tibial nerve stimulation: a qualitative study of women’s experiences. BMC Women’s Health, 21(1), 1–9.
• Davidson, E. R. W., Miceli, L., & Propst, K. (2022). Why Patients Fall Through the Cracks: Assessment of Patients’ Overactive Bladder Treatment. Journal of Women’s Health, 31(9), 1314–1319.
• Minassian, V. A., Devore, E., Hagan, K., & Grodstein, F. (2013). Severity of urinary incontinence and effect on quality of life in women by incontinence type. Obstetrics & Gynecology, 121(5), 1083–1090.