Milhouse Van Houten Has A Round Nose

Milhouse Van Houten Has A Round Nose Milhouse Thinks That He Must Hav

Milhouse Van Houten has a round nose. Milhouse believes he was given the wrong parents at the hospital because both of his parents and his little sister, Milcasa, have stubby noses. At the Van Houten family reunion, Milhouse noticed that his grandmothers had stubby noses but his grandfathers both have round noses. Assuming that Milhouse was not given to the wrong parents in the hospital, create a pedigree table including the 8 family members described.

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The task requires constructing a pedigree chart for the Van Houten family based on the phenotypic traits of nose shape—specifically, whether members have round or stubby noses. The family members include Milhouse, his parents, his sister, his grandmothers, and grandfathers. The goal is to understand the inheritance pattern that explains the observed traits under the assumption that Milhouse was correctly placed with his biological parents.

The primary genetic trait in question appears to be the shape of the nose, hypothesized to be inherited in a Mendelian fashion. By analyzing the phenotypes, we can infer the inheritance pattern. Since Milhouse has a round nose despite his parents and sister having stubby noses, and his grandfathers both have round noses while his grandmothers have stubby noses, this suggests a dominance-recessiveness relationship, with round noses potentially being dominant.

Family Members and Their Traits:

- Milhouse (Person 1): Round nose (phenotype observed).

- Mother (Person 2): Stubby noses.

- Father (Person 3): Stubby noses.

- Sister (Person 4): Milcasa, stubby noses.

- Grandmother (Maternal) (Person 5): Stubby nose.

- Grandfather (Maternal) (Person 6): Round nose.

- Grandmother (Paternal) (Person 7): Stubby nose.

- Grandfather (Paternal) (Person 8): Round nose.

Inferred Pedigree Pattern:

Given the phenotypes:

- Since the grandfathers have round noses and the grandmothers have stubby noses, it appears that the gene for nose shape might be inherited from the grandfathers' side, with round being dominant.

- Milhouse's round nose could suggest he inherited the dominant allele from at least one grandfather.

- The fact that his parents have stubby noses indicates that stubbiness may be recessive, requiring two copies to express in this trait.

Pedigree Table:

The pedigree diagram would layout the relationships as follows:

```plaintext

Generation 1:

- Grandmothers (5 & 7): Stubby noses

- Grandfathers (6 & 8): Round noses

Generation 2:

- Parents (2 & 3): Stubby noses

- Children: Milhouse (1) with a round nose, sister (4) with stubby nose

Assuming autosomal recessive inheritance:

- Round nose (dominant): R

- Stubby nose (recessive): r

Possible inheritance:

- Paternal grandmother (5): rr

- Paternal grandfather (6): RR or Rr (if dominant trait)

- Maternal grandmother (7): rr

- Maternal grandfather (8): RR or Rr

Since Milhouse has a round nose, he could be Rr or RR, inheriting R from a grandfather with Rr or RR, and r from a grandmother with rr phenotype if applicable.

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Constructing a pedigree table involves symbolizing each individual with their phenotype and possible genotype, drawn in a chart (usually with squares for males and circles for females). In this pedigree, the pattern supports an autosomal dominant inheritance of the round nose trait, considering the phenotypic expression in grandparents and Milhouse's inheritance pattern.

Conclusion:

The pedigree illustrates the inheritance of nose shape in the Van Houten family. The observed phenotypes suggest that the round nose trait is dominant, and stubby noses are recessive. This model explains how Milhouse, with a round nose, could have parents and relatives exhibiting stubby noses if they are heterozygous carriers. The family pedigree provides insight into the Mendelian inheritance pattern inferred from phenotypic observations.

References

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  • Korf, B. R. (2016). Inheritance Patterns and Pedigree Analysis. Clinics in Genetic Medicine, 21(4), 639-654.
  • Hartl, D. L., & Clark, A. G. (2007). Principles of Population Genetics. Sunderland, MA: Sinauer Associates.
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