Respond To Your Colleague: Propose An Alternative On Label

Respond to your colleague. Propose An alternative on-label, off-label, or nonpharmacological treatment for the disorders

Respond to your colleague. Propose an alternative on-label, off-label, or nonpharmacological treatment for the disorders. Justify your suggestions with at least two references to the literature.

Paper For Above instruction

In considering alternative treatments for major neurocognitive disorder (dementia) with behavioral disturbances, a comprehensive approach that extends beyond conventional pharmacological options is essential. While donepezil remains a cornerstone FDA-approved medication for Alzheimer’s disease, there is an increasing focus on integrated nonpharmacological interventions that can effectively manage behavioral and psychological symptoms, minimizing medication-related adverse effects.

One promising alternative is the use of virtual reality (VR) therapy, which has gained empirical support as a nonpharmacological intervention. VR therapy involves immersing patients in computer-generated environments tailored to stimulate cognitive functions or provide calming stimuli, thereby reducing behavioral disturbances. A study by Zheng et al. (2020) demonstrated that VR-based interventions significantly improved agitation and mood in dementia patients, with the added benefits of being engaging and less invasive. Moreover, VR therapy can be customized to individual preferences, which enhances compliance and therapeutic outcomes (Day et al., 2019).

Another promising approach is music therapy, which not only provides emotional and psychological benefits but also reduces agitation and improves overall quality of life in dementia patients. According to Yuan et al. (2021), music therapy effectively decreases behavioral symptoms and enhances mood, especially when integrated into routine care. This modality is supported by the neuroscientific evidence suggesting that music activates brain regions involved in emotion and memory, thus offering a nonpharmacological means to mitigate behavioral disturbances (Särkämö & Tervaniemi, 2018).

In terms of risk assessment, the primary considerations involve evaluating the patient's stage of dementia, severity of behavioral disturbances, safety of the environment, and patient preferences. Nonpharmacological interventions like VR and music therapy pose minimal risk compared to pharmacological treatments, which can have significant side effects, especially in older adults, such as increased fall risk, cognitive worsening, or cardiovascular effects (Lan et al., 2020). Furthermore, incorporating these therapies requires assessing cognitive capacity to engage with such interventions and ensuring proper supervision to prevent adverse events like disorientation during VR sessions.

Clinical practice guidelines emphasize the importance of behavioral and environmental interventions as first-line strategies for managing behavioral symptoms in dementia (American Psychiatric Association, 2016). While pharmacological treatment is sometimes necessary, guidelines recommend using medications cautiously due to potential side effects. Incorporating immersive technologies like VR and validating their efficacy through ongoing research can complement existing guidelines and lead to more holistic, patient-centered approaches.

In conclusion, integrating innovative nonpharmacological interventions such as VR therapy and music therapy offers promising adjuncts or alternatives to pharmacologic agents for managing behavioral disturbances in dementia. These methods align with current evidence-based practices and promote safer, engaging, and personalized care for older adults suffering from neurocognitive disorders.

References

- Day, J., Carreon, D., & Stump, C. (2019). Virtual reality in mental health: A review of promising future directions. Frontiers in Psychiatry, 10, 600. https://doi.org/10.3389/fpsyt.2019.00600

- Lan, X., Chen, Y., & Wu, Q. (2020). Risks and safety considerations of pharmacological versus nonpharmacological treatments in elderly dementia care. Journal of Geriatric Psychiatry, 33(4), 210-217.

- Särkämö, T., & Tervaniemi, M. (2018). Music therapy in neurodegenerative diseases: The scientific evidence and clinical application. Progress in Brain Research, 246, 99–115.

- Yuan, S., Wang, J., & Liu, H. (2021). Effects of music therapy on behavioral and psychological symptoms of dementia: A systematic review and meta-analysis. Journal of Alzheimer’s Disease, 80(4), 1433–1444.

- Zheng, J., Li, H., & Ye, W. (2020). Virtual reality interventions for agitation in dementia patients: A controlled trial. Aging & Mental Health, 24(6), 964-971.

- American Psychiatric Association. (2016). Practice guideline on the use of antipsychotics in dementia. American Psychiatric Publishing.