Week Three Discussions And Responses ✓ Solved

Week Three Discussions and Responses

Assignment Instructions: Respond to each classmate’s article in one or two paragraphs, providing thoughtful analysis, insights, or constructive feedback related to the topics discussed. Responses should be well-developed, showing comprehension of the material and its implications.

Sample Paper For Above instruction

Response to Monica Belton's Discussion on Calorie Restriction and Aging

Monica presents an intriguing overview of how calorie restriction may contribute to longevity and reduce the incidence of age-related diseases such as cancer, diabetes, and heart disease. She effectively highlights current research supporting the premise that reducing caloric intake can slow metabolism, diminish damage from free radicals, and potentially extend lifespan. Her mention of the study involving middle-aged adults demonstrates tangible benefits, including reductions in body fat and thyroid hormones like T3, which are associated with aging processes. While much of the research stems from animal studies, her cautious optimism about human applications aligns with current scientific discourse. Nonetheless, implementing calorie restriction for longevity must be balanced with nutritional adequacy to prevent adverse effects such as malnutrition. Ultimately, her emphasis on lifestyle adjustments like healthier eating and exercise underscores the importance of behavioral change in achieving health span extension.

Response to Christina Sanchez's Discussion on Circadian Rhythms and Metabolism

Christina provides a comprehensive summary of how resting calorie expenditure varies throughout the day, influenced by circadian rhythms. Her explanation of circadian clocks affecting metabolism and energy expenditure emphasizes the importance of maintaining regular sleep-wake schedules for optimal health. The connection between disrupted circadian rhythms—caused by shift work, irregular sleep habits, or jet lag—and metabolic disturbances underscores the potential for lifestyle modifications to improve metabolic health. Her included explanation of circadian biology clarifies how internal biological clocks regulate energy consumption and alertness, which has implications for weight management and metabolic disorders. Her recommendation to maintain consistent routines can help synchronize biological processes, possibly reducing the risk of metabolic diseases associated with circadian disruption. Overall, her insights align with current research highlighting the significance of chronobiology in metabolic health.

Response to Robert Ledford's Discussion on Stem Cell Therapy for Parkinson's Disease

Robert discusses an innovative experimental approach for Parkinson’s disease involving pluripotent stem cell injections to regenerate dopamine-producing neurons. His summary captures the essence of this cutting-edge research conducted at Kyoto University, offering hope for treating a debilitating neurodegenerative disorder. The approach of reprogramming stem cells to replace lost dopamine neurons addresses the core pathology of Parkinson’s, and the use of immune suppression medications reflects thoughtful consideration of transplant rejection risks. While promising, this research is still preliminary, with ongoing clinical trials necessary to establish safety and efficacy. The potential to restore motor function and improve quality of life makes this a highly anticipated therapeutic avenue. Overall, Robert effectively highlights how regenerative medicine could revolutionize Parkinson’s treatment and the importance of continued research in this area.

References

• Weiss, E., et al. (2018). Live Longer: The One Anti-Aging Trick That Works. Science News.
• Zitting, K., et al. (2018). Human resting energy expenditure varies with circadian phase. Current Biology, 28(22), 3524-3530. doi:10.1016/j.cub.2018.10.005
• Rettner, R. (2018). Can injecting millions of stem cells into the brain treat Parkinson’s disease? Live Science.
• Weiss, E., et al. (2018). Live Longer: The One Anti-Aging Trick That Works. Science News.
• Zitting, K., et al. (2018). Human resting energy expenditure varies with circadian phase. Current Biology, 28(22), 3524-3530. doi:10.1016/j.cub.2018.10.005
• Rettner, R. (2018). Can injecting millions of stem cells into the brain treat Parkinson’s disease? Live Science.
• Hood, S., & Amir, S. (2017). The aging clock: Circadian rhythms and aging. Science, 355(6332), 1253-1258.
• Buxton, O. M., et al. (2012). Sleep and metabolic function. Progress in Brain Research, 199, 231-241.
• Hoffmann, A. (2016). Calorie restriction: The anti-aging diet. Geroscience, 38, 15-25.
• Sharma, S., et al. (2019). Advances in stem cell therapy for neurodegenerative diseases. Cellular and Molecular Life Sciences, 76(5), 887-902.