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Respond to the following: Christie Artuso 6:33 PM Another famous study with similar ethical breaches occurred several years before. You may be familiar with the Tuskegee Study and its failure to obtain consent, as well as dishonest information that was provided. This study was not fully investigated until the early 1970's...and yet it began in the 1930's. Compare and contrast Henrietta Lack's ethical breach (HeLa cells) and the Tuskegee Study.
Paper For Above instruction
The comparison between Henrietta Lacks' ethical breach involving the use of her cells and the Tuskegeee Syphilis Study reveals profound differences and similarities in ethical considerations within biomedical research. Both incidents highlight serious violations of research ethics, yet they stem from distinct contexts and ethical lapses.
The Tuskegee Syphilis Study, conducted by the U.S. Public Health Service between 1932 and 1972, involved deceiving African American men by withholding treatment for syphilis without their informed consent. The study aimed to observe the natural progression of untreated syphilis, neglecting the participants' rights, health, and dignity. The researchers did not inform participants about their diagnosis or the purpose of the research, violating fundamental ethical principles such as respect for persons and beneficence. The ethical breach was compounded by deliberate misinformation and lack of informed consent, which later spurred reforms in research ethics and the establishment of institutional review boards (Freimuth et al., 2001).
In contrast, Henrietta Lacks' case involved the collection of her cancer cells without her knowledge or consent in 1951. These cells, later known as HeLa cells, became a breakthrough in scientific research. While her cells were used extensively for decades without her or her family's knowledge, the ethical breach was less about intentional deception and more about systemic neglect of patients' rights and informed consent. Unlike the Tuskegee study, which was an ongoing experiment with malicious intent, the use of HeLa cells was initially a clinical practice, reflective of a period when patient awareness of biological specimens' use was minimal. Over time, ethical standards have improved, but her case highlighted the need for informed consent and respect for individual autonomy in research (Skloot, 2010).
Both cases underscore the importance of ethical oversight in biomedical research. The Tuskegee Study exemplifies gross misconduct and blatant disregard for human rights, leading to legal and ethical reforms. In comparison, Henrietta Lacks' case illustrates systemic issues regarding consent and recognition, prompting ongoing discussions about ethics in tissue collection and commercialization (Lembo & Boulware, 2017). Recognizing these differences helps inform current ethical standards, emphasizing respect, transparency, and participant autonomy.
References
- Freimuth, V. S., Quinn, S. C., Thomas, S. B., Cole, G., Zook, E., & Daniels, N. (2001). African Americans' views on research and the Tuskegee Syphilis Study. American Journal of Public Health, 91(1), 171-177.
- Skloot, R. (2010). The Immortal Life of Henrietta Lacks. Crown Publishing Group.
- Lembo, N. J., & Boulware, L. E. (2017). The history and ethics of Henrietta Lacks' biological materials. The New England Journal of Medicine, 377(16), 1487-1489.