Select A Neurological Disease Or Hormonal Alteration

Select A Neurological Disease Or Alternation Of Hormonal Regulation Co

Select a neurological disease or alteration of hormonal regulation covered in chapters 16 or 20 (e.g., Parkinson’s disease, Alzheimer’s disease, diabetes mellitus, hyperthyroidism, or any other hormonal disorder covered in these chapters). Research to find additional information that was not presented in the text to share with the class for a better understanding of the diseases, effective treatments, and recommended nursing interventions. 150 words count.

Paper For Above instruction

Alzheimer’s disease is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes. While the pathophysiology involves amyloid plaques and neurofibrillary tangles, recent research suggests a role of inflammation and vascular factors in disease progression. Additional information indicates that early diagnosis involves cognitive assessments and imaging techniques such as PET scans to detect amyloid deposits. Pharmacological treatments include acetylcholinesterase inhibitors like donepezil and NMDA receptor antagonists like memantine, which temporarily improve symptoms but do not halt progression. Non-pharmacological interventions encompass cognitive therapies, physical activity, and social engagement to maintain functional abilities. Nursing interventions focus on patient safety, emotional support, and education for caregivers regarding disease progression and managing behavioral symptoms, such as agitation and wandering. Emerging research into neuroinflammation and lifestyle modifications presents promising avenues for enhancing care and delaying disease progression.

References

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2. Cummings, J., et al. (2020). Alzheimer's disease drug development pipeline: 2020. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 6(1), e12050.

3. Long, J. M., & Holtzman, D. M. (2019). Alzheimer Disease: An update on pathobiology and treatment strategies. Cell, 179(2), 312-339.

4. WHO. (2023). Dementia Fact Sheet. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/dementia

5. Kumar, A., & Singh, A. (2019). Pharmacological approaches to Alzheimer's disease. Current Neuropharmacology, 17(10), 1074-1084.

6. Livingston, G., et al. (2020). The Lancet Commission on dementia prevention, intervention, and care. Lancet, 396(10248), 413-446.

7. Reitz, C., & Mayeux, R. (2014). Alzheimer’s disease: Epidemiology, diagnostic criteria, risk factors, and biomarkers. Biological Psychiatry, 75(7), 530-536.

8. Cummings, J. L. (2019). Lessons learned from Alzheimer disease: Clinical trials and the future. JAMA Neurology, 76(4), 439-439.

9. Jack, C. R., et al. (2018). NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease. Alzheimer's & Dementia, 14(4), 535-562.

10. Prince, M., et al. (2015). World Alzheimer report 2015: The global impact of dementia. Alzheimer’s Disease International.